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Archives: Analytes

Melatonin Saliva Collection

Print Approved Collection Methods Passive Drool Special Considerations Melatonin can be obtained over the counter as a supplement, and such supplementation should be documented. Melatonin levels in saliva are highly dependent on a diurnal pattern of melatonin production. Levels are low during daylight hours and may not be detectable within hours of daylight onset. Levels [...]

Interleukin-6 Saliva Collection

Print Approved Collection Methods Passive Drool Special Considerations Studies show that levels of IL-6 in the oral fluid of healthy individuals do not reflect the levels of IL-6 in circulation. Levels of IL-6 in saliva may only represent individual differences in the degree of inflammation in the oral mucosal immune compartment. This analyte is sensitive [...]

Interleukin-1 Beta Saliva Collection

Print Approved Collection Methods Passive Drool SalivaBio Swabs Special Considerations Studies show that levels of IL-1 Beta in the oral fluid of healthy individuals do not reflect the levels of IL-1 Beta in circulation. Levels of IL-1 Beta in saliva may only represent individual differences in the degree of inflammation in the oral mucosal immune [...]

Insulin Saliva Collection

Print Approved Collection Methods Passive Drool SalivaBio Swabs Special Considerations Fasting insulin levels in saliva correlate well with levels in serum. If fasting insulin levels are of interest, do not consume food or beverage within eight hours prior to saliva collection. If insulin levels following a glucose challenge are of interest, please be advised that [...]

IL-8 Saliva Collection

Print Approved Collection Methods Passive Drool Special Considerations Studies show that levels of IL-8 in the oral fluid of healthy individuals do not reflect the levels of IL-8 in circulation. Levels of IL-8 in saliva may only represent individual differences in the degree of inflammation in the oral mucosal immune compartment. This analyte is sensitive [...]

Estrone Saliva Collection

Print Approved Collection Methods Passive Drool Special Considerations Estrogens are components of various medications and use of these substances can influence the levels measured in saliva. The medications may be delivered via gels, oral tablets, and inhalers. Document use of estrogen containing contraceptives. This analyte is sensitive to freeze-thaw degradation. Sample collection, storage, and handling [...]

Estriol Saliva Collection

Print Approved Collection Methods Passive Drool Special Considerations Estrogens are components of various medications and use of these substances can influence the levels measured in saliva. The medications may be delivered via gels, oral tablets, and inhalers. Document use of estrogen containing contraceptives. This analyte is sensitive to freeze-thaw degradation. Sample collection, storage, and handling [...]

Estradiol Saliva Collection

Print Approved Collection Methods Passive Drool Special Considerations Estrogens are components of various medications and use of these substances can influence the levels measured in saliva. The medications may be delivered via gels, oral tablets, and inhalers. Document use of estrogen containing contraceptives and consider recording the menstrual cycle day count or equivalent. This analyte [...]

DHEA-S Saliva Collection

Print Approved Collection Methods Passive Drool Special Considerations DHEA(S) is available over the counter in some areas as a supplement. Document use within 12 hours prior to sample collection. Unlike DHEA, levels of DHEA-S in saliva do not correlate as highly with serum levels. This analyte is sensitive to freeze-thaw degradation. Sample collection, storage, and [...]

DHEA Saliva Collection

Print Approved Collection Methods Passive Drool Special Considerations DHEA(S) is available over the counter in some areas as a supplement. Document use within 12 hours prior to sample collection. This analyte is sensitive to freeze-thaw degradation. Sample collection, storage, and handling should be carefully designed to minimize the impact of freeze-thaw cycles. Consider documenting parameters [...]

Cotinine Saliva Collection

Print Approved Collection Methods Passive Drool SalivaBio Swabs Special Considerations Salimetrics cotinine assay is designed to be highly sensitive so that discrimination can be made between primary and secondary tobacco smoke exposure.  However, levels of cotinine in known heavy smokers will be outside of Salimetrics’ assay range and must be assayed after dilution. Cotinine is [...]

C-Reactive Protein Saliva Collection

Print Approved Collection Methods Passive Drool Special Considerations Levels of CRP are expected to be low and stable across time unless the donor has a systemic infection.  In the latter case, levels of CRP in saliva may be extremely high. This analyte is sensitive to freeze-thaw degradation. Sample collection, storage, and handling should be carefully [...]

Androstenedione Saliva Collection

Print Approved Collection Methods Passive Drool Special Considerations Consider documenting parameters to estimate saliva flow-rate (ie; time taken to collect and sample volume). Consistency in collection method is recommended to avoid introducing unsystematic error into your study data. Saliva Collection Protocol Before Sample Collection Avoid foods with high sugar, acidity, or caffeine immediately before sample [...]

Alpha-Amylase Saliva Collection

Print Approved Collection Methods Passive Drool SalivaBio Swabs Special Considerations Consider documenting parameters to estimate saliva flow-rate (ie; time taken to collect and sample volume). Consistency in collection method is recommended to avoid introducing unsystematic error into your study data. If collecting with swab devices, it is important to know that concentrations of this analyte [...]

Aldosterone Saliva Collection

Print Approved Collection Methods Passive Drool Special Considerations Licorice (real) mimics aldosterone and should be avoided 2 weeks before collection. Posture affects aldosterone levels. We recommend sampling after 30 minutes in a resting position. Saliva Collection Protocol Before Sample Collection Avoid foods with high sugar, acidity, or caffeine immediately before sample collection. Document consumption of [...]
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