It appears that your browser may be outdated and performance may be limited. The My Study builder is best viewed with the latest internet browsers. However, if you’d prefer to use our standard form, you can access it below.

Go to Internet Explorer Quick Quote Form

Dismiss this message

Salivary Bioscience News

Longitudinal Salivary Cortisol Study Evaluates Theory of Developmental Origins of Health & Disease

Assessment of the cortisol awakening response: Expert consensus guidelines.

Author: Winchester SB, et al (2015). Res Nurs Health.

In a prospective, case-controlled longitudinal design, 180 preterm and full-term infants who had been enrolled at birth participated in a comprehensive assessment battery at age 23. Of these, 149 young adults, 34 formerly full-term and 115 formerly preterm (22 healthy preterm, 48 with medical complications, 21 with neurological complications, and 24 small for gestational age) donated five saliva samples from a single day that were assayed for cortisol to assess diurnal variation of the hypothalamic-pituitary-adrenal (HPA) axis. Analyses were conducted to determine whether prematurity category, birth weight, and socioeconomic status were associated with differences in HPA axis function. Pre- and perinatal circumstances associated with prematurity influenced the activity of this environmentally sensitive physiological system. Results are consistent with the theory of Developmental Origins of Health and Disease and highlight a possible mechanism for the link between prematurity and health disparities later in life.

View Abstract

Keywords: NICU, allostatic load, disparities, diurnal cortisol, hypothalamic-pituitary-adrenal axis, neonatal care, preterm infants

*Note: Salimetrics provides this information for research use only (RUO). Information is not provided to promote off-label use of medical devices. Please consult the full-text article.

WordPress Cookie Plugin by Real Cookie Banner
Contact: Salimetrics (USA)
View All International Distributors

ENGAGE – in the Saliva Research Collaboratory

Work one-on-one with Dr. Douglas Granger, a distinguished salivary bioscience researcher, to advance and refine your ideas, problem solve research design issues, pre-review proposal concepts, and rework plans for grant resubmissions.

Learn More

CALL 800.790.2258